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A workaholic research physician specializing in infectious diseases, Mueller is most at home in her epidemiology lab and has neither the time nor the desire for a serious romantic relationship. But she begins to reconsider when she meets Jack Ryan.
Cathy Mueller first meets Jack Ryan at her father's birthday party. She doesn't get to know him very well because he's whisked away by a helicopter. Cathy works at Washington Memorial Hospital and specializes in infectious diseases. She is visited by Jack and gives him her number. The two of them go out on a date and after she invites him back to her place. Cathy investigates an Ebola strain that she thought had been eradicated. She is taken to talk with CIA officials after having sent an e-mail to her superiors about the strain. This is when she learns that Jack isn't just an ordinary analyst but works for the CIA. She gets mad at him because he lied to her. Later, Jack invites her to dinner where he explains everything to her. She decides to give him another chance. When Jack suspects that Suleiman is going to attack the hospital, he calls Cathy. Cathy gets his text message and tries to evacuate the hospital but Secret Service says that they must get higher officials like the President out first. Cathy pulls the fire alarm going against Secret Service protocol. Cathy is taking the elevator down when Dudayev gets on. She plays it cool and luckily is saved by Greer, who shoots Dudayev when the elevator door opens.
- Like her love interest, Jack Ryan, Cathy Mueller has appeared in numerous other Tom Clancy-fueled realities.
- In those previous appearances (and books), “Cathy was an ophthalmic surgeon at the Wilmer Eye Institute of Johns Hopkins University School of Medicine and a Professor of Surgery at Johns Hopkins.” That quote is from the Fandom page for ‘Caroline "Cathy" Ryan.’
- Depicted in Amazon Prime's Jack Ryan during the earliest stages of her relationship with Ryan, she has typically been seen as either his fiancée or wife in other productions.
- Pilot (First appearance)